Generic name for Relafen is nabumetone.
Relafen is a group of drugs called anti-inflammatory nonsteroidal (NSAID).Relafen is used to treat pain or inflammation caused by arthritis. Relafen works by reducing hormones that cause inflammation and pain in the body.RELAFEN (nabumetone) is a naphthylalkanone designated chemically as 4-(6-methoxy-2-naphthalenyl)-2-butanone. Nabumetone is a greyish-white crystalline substance with a molecular weight of 228.3. It is nonacidic and practically insoluble in water, but soluble in most organic solvents and alcohol. It has an n-octanol: phosphate buffer at pH 7.4 2400 coefficient. The main compound is a prodrug, which suffers from liver biotransformation for the active component, acid 6-methoxy-2-naphthylacetic (6MNA), which is a potent inhibitor of prostaglandin synthesis.
Relafen is acid and n-octanol: phosphate coefficient of 0.5 to fraction of 7.4 buffer. Free pH depends on the total concentration of 6MNA and is proportional to the dose in the range of 1,000 to 2,000 mg mg. It is 0.2% to 0.3%, to own concentrationsNabumetone not detected in the plasma. Approximately 35% of an oral dose of 1000 mg nabumetone becomes 6MNA and 50% turns into unidentified metabolites which are then excreted in the urine. 6MNA is more than 99% plasma protein. 6MNA presented pharmacokinetic characteristics that generally follow a model of a compartment with the first order of entry and elimination.
Relafen medication should not use certain medical conditions. Relafen cause stomach bleeding. Daily use of alcohol and tobacco, mainly when combined with this medicine, may increase the risk of stomach bleeding. Before using Relafen tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease and poorly controlled diabetes. Check all prescription and sale of medicine labels carefully since many contain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen or naproxen) pain, which are similar to the drug. Before use Relafen consult your doctor or pharmacist if you have: asthma sensitive to aspirin, recent heart bypass surgery.
Relafen drug uses
Relafen can be taken with or without food. Take the dose as soon as you forgotten. Never take a double dose.It can be stored at room temperature and keep this medication in the container arrived, hermetically closed in humid places and direct light.
Relafen side effects medication
Effects can not be anticipated. Relafen medication side more serious common include effect is abdominal pain, constipation, diarrhea, dizziness, retention of liquid, gas, headache, indigestion, itching, nausea, skin rashes and ringing in ears. These effects are considered serious Relafen.
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