It is a life-threatening allergic reaction to specific triggers such as food, medicine, latex or insect venom. Although there is no complete information, the best statistics indicate 40.9 million people in the United States suffer from serious allergies which can put at risk of anaphylaxisand numbers are growing.1 10,28 anaphylactic symptoms may include difficulty breathing or swallowing, hives or swelling around the mouth or eyes. Anaphylaxis can be treated successfully with epinephrine, but patients must be on alert for a secondary reaction that occur in the hours after the initial attack, a biphasic reaction.
Definition
Anaphylaxis or anaphylactic shock, is an allergic reaction that can be fatal in a matter of minutes, either through inflammation shuts airways or by a dramatic fall in blood pressure.
Anaphylaxis occurs in individuals when they are exposed to an allergen that are allergic. An allergen is a protein which is treated by the immune system as a substance almost always overseas. Get in contact with or ingestion of this allergen triggered a chain reaction in the immune system of a person that can lead to inflammation of the airways, loss of blood pressure and loss of consciousness, resulting in anaphylactic shock.
The function of the immune system is to protect the body from foreign invaders.
Some anaphylactic reactions involve only an organ system, such as the respiratory tract and skin. However, anaphylaxis, various systems are usually affected simultaneously. This includes the upper part and gastrointestinal, cardiovascular and respiratory system.
Respiratory tract begins with the nose and ends with the lungs. It is responsible for bringing fresh oxygen to the blood and remove waste from the body of carbon dioxide.
The cardiovascular system is the heart and many blood vessels, veins and arteries. This system pumps blood throughout the body, delivering fresh oxygen and waste disposal.
The gastrointestinaI tract extends from the mouth to the anus. It is responsible for receiving food, digesting nutrients, absorb nutrients into the bloodstream and also remove waste products from the body.
In essence, the immune system in people with allergies perceived allergens (e.g. food, medicines, rubber latex, insect venom proteins) as foreign substances that are fattened or sensitized to react against their bodies. More specifically, the part of the immune system that is usually involved in the fight against the proteins of the forms of strange organisms called IgE antibodies that sit on the surface of the specialized cells of the mast. Mast cells are full of chemicals called mediators as histamine and leukotrienes, which are released when the allergenic protein reacts with the antibody IgE.
The release of these mediators of IgE causes:
Contraction of smooth muscle found in the respiratory and gastrointestinal tract, which can cause gastrointestinal symptoms and wheezing (cramps, vomiting, nausea, or diarrhea) Vascular dilation which can cause swelling (angioedema), hives (urticaria), and a decrease in the volume of fluid from the blood that can lead to shock Fortunately, effective treatment is available, so the death of anaphylaxis can be avoided in most cases. Still, needless deaths occur every day because anaphylaxis symptoms go unrecognized or because the treatment is not fast enough.
Symptoms
The most characteristic symptoms of anaphylaxis include:
Hives, swelling of the throat, lips, tongue, or around the eyes can include difficulty breathing or swallowing other common symptoms of anaphylaxis:
Metallic taste or itching in the mouth Generalized redness, itching or redness of the skin, cramping abdominal, nausea, vomiting or diarrhoea increased heart rate sudden decrease in blood pressure (and accompanying pallor) sudden feeling of weakness anxiety or an overwhelming sense of doom collapse loss of consciousness statistical anaphylaxis
The number of people in the United States with Allergic sensitivity that put them at risk of anaphylaxis can be as high as 40.9 million.28 real impact is unknown, but it is believed that you low - notify as anaphylaxis are often confused with the attacks of asthma and other respiratory emergencies.
The following statistics can help you better understand who is affected by anaphylaxis and the importance of dealing with epinephrine.
Risk of anaphylaxis
There are 1.3 million and 13 million people who are allergic to insect stings.3, 11 each year, 40 to 400 anaphylactic deaths occur from insects, stings.1, 11-13 in people who have had a reaction to an insect bite, 30% to 60% have a reaction of repetition which is so severe or more severe than the first episode.14 food allergies affect 5.4 million to 7 million people.2 the incidence of allergies in children food is increasing.6 more than 2 million, or 8 per cent of children under the age of three years the U.S. has allergies.16 of food, there are three million, or 1.1%, Americans who are allergic to peanuts or nuts.2 trees each year, 125 deaths are attributed to food-related anaphylaxis.17 there are 2.7 million to 16 million people who are allergic to latex.910,18 in health-care workers, 8% and 17% are latex sensitive.7, 8, 18 to 27 million people, 0.7% to 10%, is allergic to penicillin is responsible for approximately 5,440 cases fatal anaphylaxis per year, which represents approximately 75% of U.S. anaphylaxis deaths.1, 20 most of the deaths occur among those without asthma drug allergies.1 background are at special risk to experience penicillin.19 anaphylaxis.1
Incidence
Anaphylaxis occurs at a rate of 21 per 100,000 people each year in the northern United States21 almost 82,000 episodes of anaphylaxis can occur each year in the United States22 more than 57,000 Americans may experience anaphylaxis each year.22 importance of the implementation and use of epinephrine
In a study of children and adolescents, 10 of 13 fatal or near fatal anaphylactic reactions occurred within the home.23 none of the deceased had epinephrine with them; all the deaths-no received epinephrine before or within 5 minutes of developing severe anaphylaxis speed symptoms.23 potentially fatal
Only 1 to 2 minutes for an allergic reaction mild reach faster anaphylaxis.24 the beginning of an anaphylactic reaction, the greater the probability that is biphasic reaction severe.1
25% Of people who have an anaphylactic reaction experienced a recurrence in the hours after the start of the reaction and require greater medical treatment, including epinephrine additional injections.25-27 this delayed reaction is called biphasic, which means two phases. For more information, visit: http://www.epipen.com
EPI pen is writer for treatment of allergic reactions and medications, allergies, anaphylaxis, anaphylaxis, symptoms of anaphylaxis reactions and treatments of emergency reaction, anaphylaxis. EpiPen injector http://www.epipen.com/
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